BMT Program History

On July 1, 1987, Kenneth F. Mangan, M.D., founded and established the Temple University Bone Marrow Transplant Program at 2400 North Broad Street. The program received an official State of Pennsylvania Certificate of Need early in 1988.

First autologous BMT was 2/28/88
First allogeneic BMT was 11/16/89
First autologous PBSCT was 5/16/90
First allogeneic PBSCT was 3/14/96
First matched unrelated donor BMT was 12/6/96
First submyeloablative, mini-allogeneic PBSCT was 5/18/99
BMT program moved to the Jeanes campus in Northeast Philadelphia on 4/1/2000
Over 1000 transplants performed by 2008

Transplant Activity

Over 650 autologous blood or marrow stem cell transplants
Over 350 allogeneic blood or marrow stem cell transplants
Recent transplant activity is over 80 transplants per year
Matched related and matched unrelated allogeneic transplants using full myeloablative or submyeloablative regimens
Over 2000 apheresis procedures for stem cell collection
Capable of purging with photoactive dyes and performing positive CD-34 stem cell selection
Over 50 donor lymphocyte infusions for treatment of relapse
Over 125 total body irradiation procedures

Special Strengths and Extensive Experience

Transplants for patients with acute and chronic leukemia and preleukemia (myelodysplastic syndrome)
Extensive experience for transplants of all kinds in patients with various lymphomas, Hodgkin's disease and multiple myeloma
Special programs for treatment of patients with severe aplastic anemia and related marrow failure states
An autologous stem cell program for treatment of amyloidosis
Complete, extensive consultation reports to patients and referring physicians for initial and all subsequent visits
Extensive experience with mini-allogeneic transplants and donor lymphocyte infusions

Credentials/Certifications

State of Pennsylvania Certificate of Need (1998)
Level I Accredited by the Foundation for Accreditation of Cellular Therapy. Reaccredited in 2008.
Eastern Cooperative Oncology Group Transplant Center
Bone Marrow Transplant Clinical Trails Network Center
An approved and certified transplant and stem cell collection center for the National Marrow Donor Program
Member in good standing of the International Bone Marrow Transplant Registry

Committees and IRB

Every protocol is approved by Temple University and/or Fox Chase Cancer Center Research Review
Approved protocols may also be independently reviewed by the Physicians Data Query for the National Cancer Institute
We participate in cooperative group protocols, pharmaceutical protocols, and investigator-initiated protocols

E-mail this page

Print this page